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The most common side effects in those who have diabetes are low blood sugar ( hypoglycemia ), headache, back pain, cough, and fatigue. How it works: Contrave is a combination of two FDA-approved drugs, naltrexone and bupropion, in an extended-release formula. Side effects: The most common side effects include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Sleep Loss Tied to Changes in Gut Bacteria. The appeal of losing weight quickly is hard to resist. Colon Cancer on the Rise Among Young Adults. And are they a safe option for weight loss. Video: Cancer Takes a Toll on a Small Town. What else you should know: You should be on a low-fat diet (less than 30% of your daily calories from fat) before taking orlistat. They do not work for everyone, and their benefit may be modest. Also, take a multivitamin at least 2 hours before or after taking orlistat, because the drug temporarily makes it harder for your body to absorb vitamins A, D, E, and K. For some people, prescription weight loss drugs may help. Before you get a weight loss drug prescription, tell your doctor about your medical history. Bupropion is approved to treat depression, seasonal affective disorder, and help people stop smoking. Over-the-counter weight-loss pills The temptation to use over-the-counter weight-loss pills to lose weight fast is strong. Eat a healthy low-calorie diet with lots of fruits and vegetables and be physically active. But they may get worse if you eat high-fat foods.


Mayo Clinic Health Letter Medical Products Population Health and Wellness Programs Health Plan Administration Medical Laboratory Services Continuing Education for Medical Professionals Giving to Mayo Clinic Give Now Your Impact Frequently Asked Questions Contact Us to Give Give to Mayo Clinic Help set a new world standard in care for people everywhere. How it works: Blocks your body from absorbing about a third of the fat you eat. But do weight-loss pills and products lighten anything but your wallet. Request an Appointment Find a Doctor Find a Job Give Now. People taking some depression medications with Belviq need to be monitored very closely for a rare but serious reaction that includes fever and confusion. But there is relatively little research about these products, and the best studied of these are prescription weight-loss drugs. Side effects include abdominal cramping, passing gas, leaking oily stool, having more bowel movements, and not being able to control bowel movements. Also, possible side effects and adverse reactions to weight-loss pills can affect the treatment outcome. Asprin: The Wonder Drug in Your Medicine Cabinet. Give now. Naltrexone is approved to treat alcohol and opioid dependence. For example, a 2014 study reviewed 21 long-term trials of prescription drugs for treating obesity. Weight-loss pills — prescription medicines, nonprescription drugs, herbal medicines or other dietary supplements — are all, at best, tools that may help with weight loss. These side effects are generally mild and temporary. Contrave has a boxed warning about the increased risk of suicidal thoughts and behaviors associated with bupropion. Clinically meaningful weight loss — enough weight loss to begin lowering the risk of cardiovascular disease, diabetes and other diseases — is generally defined as 5 percent or more of body weight. The most effective way to lose weight and keep it off is through lifestyle changes. Eating less and moving more are the basics of weight loss that lasts.

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